Clinical and technical validation studies for diagnostic companies

J Clin Microbiol. 2014 May;52(5):1672-7. Detection of nonhemagglutinating influenza a(h3) viruses by enzyme-linked immunosorbent assay in quantitative influenza virus culture. van Baalen CA, Els C, Sprong L, van Beek R, van der Vries E, Osterhaus AD, Rimmelzwaan GF....

Clinical studies and cases

  Influenza viruses & Dengue viruses   EbioMedicine / The Lancet. 2019 Jan: 9; (40): 574-582. Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2,...

Animal model development: other species / other viruses, etc.

Ferrets Rabbits Cats Non-human primates   Published online: 18 Nov 2021  Development of molecular clamp stabilized hemagglutinin vaccines for Influenza A viruses npj Vaccines (2021) 6:135 ; https://doi.org/10.1038/s41541-021-00395-4. Christopher L. D. McMillan,...

Animal model development: novel approaches

Immunocompromised ferret model In vivo imaging Rapid development of animal models for emerging viruses Viruses 2018 January; 1(10): doi10.3390/v10010018  Transmission of Human Respiratory Syncytial Virus in the Immunocompromised Ferret Model.  Leon de Waal, Saskia L....

Vaccine immunogenicity- and efficacy testing in ferrets  

.Humoral immune responses (ELISA, Virus Neutralization, Plaque Reduction, Haemagglutination Inhibition, etc. ) Cell-mediated immune responses; Prime-boost strategies; Production of hyper immune serum; Longevity of protection; Dose-finding, Dose-optimization; Clinical...
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