Antiviral efficacy and pharmaco kinetics testing in ferrets

Prophylaxis and Therapy (delayed treatment) (Deep) sequencing, mutation-specific PCR Any route of drug administration possible (IV, oral, nebulizer, etc.) Read outs include: clinical scoring (signs of disease, body temperature, lung function, etc), viral loads (by...

Antiviral efficacy testing and pk analysis in non-human primates

Prophylaxis and Therapy (delayed treatment) (Deep) sequencing, mutation-specific PCR Any route of drug administration possible (IV, oral, nebulizer, etc.) Read outs include: clinical scoring (signs of disease, body temperature, lung function, etc), viral loads (by...

Vaccine immunogenicity- and efficacy testing in non-human primates

Active- and passive immunization strategies Read outs include: antibody responses, cell-mediated immune responses, clinical scoring (signs of disease, body temperature, lung function, etc), viral loads (by quantitative PCR and virus titration), gross pathology,...
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